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In Situ Hybridization

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ISH staining
In situ hybridization (ISH) is a molecular biologic technique for revealing the location of specific DNA and RNA sequences in tissues, cells, chromosomes, or other structures by hybridizing the complementary strand of a nucleotide probe to a particular sequence. ISH and immunohistochemistry (IHC) are similar in that both use samples fixed on microscope slides and require interpretation under the microscope. However, IHC relies on protein chemistry, while ISH relies on nucleic acid chemistry for target detection.

davidjones00 156 days ago

Health | biology

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