Preparation and Custom Synthesis for H. pylori Vaccine Antigens

H. pylori vaccines antigen preparation
Ace Infectious produces multiple strains of inactivated H. pylori as whole-cell vaccine antigens. The genome of H. pylori is highly variable, with significant allelic and sequence diversity even among well-characterized strains. Therefore, the isolation and collection of H. pylori strains is a huge project. Fortunately, based on our long-term efforts in H. pylori, we have accumulated a rich collection of H. pylori strains from Africa, Asia, Europe, and the Americas. We also offer a wide range of chemical and physical inactivation methods to inactivate H. pylori, including the use of formalin, chloroform, phenol, ammonium sulfate, heat, sonication, and lysis with sodium dodecyl sulfate (SDS) or sodium hydroxide at pH 9.5. For a specific request for an inactivated H. pylori strain or inactivation method, you can consult our technical support staff.

Antigen custom synthesis for H. pylori subunit vaccines
Since obtaining specific antigens directly from H. pylori is considered unsafe and cumbersome, Ace Infectious provides multiple expression systems for the synthesis of subunit vaccine antigens to improve the safety and ensure the stability of the antigenic composition. We have four well-established antigen expression systems, namely Escherichia coli (E. coli) expression system, Lactococcus lactis (L. lactis) expression system, Pichia pastoris (P. pastoris) expression system, and attenuated Salmonella expression system.