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Homogeneity Characterization
Protein purity and homogeneity are key for protein crystallization and rigorous structural and functional studies. Impure samples will lead to inaccurate and imprecise results across experiments. In addition, Protein purity and homogeneity are two very important characteristics for further protein studies and biopharmaceutical applications. Purity of protein sample limits the application of protein products. Common contaminants of protein product include culturing medium and reagents from extraction and purification steps. In addition to impurity, protein heterogeneity may result from differential intra-cellular processing and the addition of co- and post-translational modifications. It is important to analyze the purity and homogeneity of your protein prior to using it for further processes.
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